The Dons will be guaranteed continental action for the first time for five years if they win on Saturday.
The runners-up will enter the competition in the second qualifying round while the third-placed team - currently Motherwell - will begin at the first round stage.
Should the Dons finish second behind Celtic, they will have to play three two-legged ties in order to reach the Europa League group stages.
McInnes told the Evening Times: "I have a fully committed, honest group of players who are going to do all they can to secure Europe.
"Bringing European football back to Aberdeen is important and on Saturday we can achieve that.
"My players are a really honest, hard working bunch of boys and they have done so well for me this season. Now we all want to finish off the season with a strong ending."