Palace have slipped four points adrift of Cardiff after winning just one of their last six Championship games, drawing four.
However, Bluebirds manager Mackay is well aware of the talent that counterpart Ian Holloway has at his disposal.
"Palace have quality players in a squad who have been together for a fair time. They are capable of causing problems, but we have plenty of quality as well," said Mackay, who expects the sold-out Cardiff City Stadium to be in full voice for the match.
"Our supporters will turn out in force again and the atmosphere is going to be fantastic. The whole stadium will be rocking," he added on Wales Online.