City had sealed qualification for the knockout stages even before their last outing in the competition, a 4-2 home win over Czech outfit Viktoria Plzen.
And it was a real landmark achievement for the club, with it being the first time the Blues - now in their third Champions League campaign, having debuted in 2011-12 - have managed to progress beyond their group.
Overhauling leaders Bayern to ensure progress as Group D winners would be a great way for City to round off their efforts in the pool, but it is a tall-looking order to say the least.
The defending champions have registered victories in all five of their group games, including a dominant 3-1 win at City, who are three points behind the German side and would need to better that result in the Allianz Arena to leapfrog them.
Blues boss Manuel Pellegrini is in no doubt that it will be a tough task, but has emphasised that his team will give their all.
"We have qualified for the next round and this is very good," the Chilean said.
"It would be better to be first in the group but we have played against a very strong team in Bayern Munich.
"They played better than our team here (in Manchester). We finish against them on Tuesday and, of course, it will be very difficult to beat them 3-0 at their ground.
"But we will try to do a very good match and we will try to win."
Pellegrini - named over the summer as successor to Roberto Mancini, who oversaw City's last two Champions League campaigns - has stressed that whatever happens on Tuesday, with qualification secured the key job has been done.
And although he was critical of the Blues' defending in the last Plzen encounter, he has praised his team's exploits in Group D overall, singling out the Bayern defeat as the only real disappointment.
City won 3-0 away against Plzen and also beat CSKA Moscow 2-1 in Russia and 5-2 at home.
And Pellegrini said: "I think through the whole group we have played well, except for in that match (against Bayern).
"We didn't do it against Bayern but that can happen.
"It is very important to be first in the group but not the most important thing.
"Our target was to qualify and we did it."