The Foxes go into their home game against Birmingham on Friday night two points behind Brighton, who currently occupy the final play-off spot following last weekend's 1-1 draw with Pearson's side.
After the visit of the Blues, Leicester face Bolton, who are level on points with Pearson's side in eighth place, Crystal Palace, Watford and Nottingham Forest - who are currently fourth, third and fifth in the table respectively.
"We've got a great opportunity to make the play-offs. We've got five games left and it is in our own hands," Pearson told reporters ahead of the Birmingham match.
"They are tough fixtures, yes. But all the games in this division are tough and they will be tough fixtures for everyone.
"It is an important part of the season and we've got five games in which to do enough ourselves, regardless of what anyone else thinks, or what any other side does. We've still got teams to play in and around us."
Meanwhile, Leicester must stop conceding late goals if they are to keep their play-off hopes alive, insists midfielder Matty James.
"We have to take positives from the Brighton game because we played really well and deserved three points," James, 21, told reporters ahead of the visit of Birmingham on Friday night.
"But we conceded very late again. We have to cut out these last-minute goals.
"We were in control of the game and it is that one little lapse which has cost us the three points. We have to go to places like Brighton and take 1-0 wins."