Victory at home to already-promoted Burnley will see the Royals secure at least sixth place, but they know they cannot afford a slip with Brighton only one point behind.
But while Burnley have already turned their thoughts to life in the Barclays Premier League next season, Nigel Adkins is not expecting an easy ride as his side bid to join Derby, QPR and Wigan in the play-offs.
"Burnley did very well when we played up at their place," he said.
"We're facing a team who's just been promoted, they will come to our place and give us nothing. We've got to be right at it.
"The mind-set has to be to win. We won our last home game, won on Saturday and showed we can come from behind.
"We'll work hard on the training ground, be right mentally and it's going to be a great day."