Brighton, who trail 2-1 from the first leg at The Amex, will take plenty of positives from their second-half display, as only the heroics of Rams keeper Lee Grant and the width of the crossbar prevented them from equalising in the first encounter.
Calderon said: "The important thing is that we are alive going into the second leg and there's only one goal in it.
"They had a bit of luck and we didn't and you need luck in these kind of games. We hit the bar and they did as well, but their shot came off Tomasz and went in.
"We still have a chance and we will fight until the last second of the game.
"It's going to be more like the second half from the first leg. We've got to score one but they are going to play on the counter-attack. Hopefully it's going to be a good game for us."
Brighton have new injury concerns over Matt Upson (ankle) and Will Buckley (hamstring).
Derby have won all three of the meetings between the two sides so far this season.
Albion's last success away to the Rams came in a Championship clash in November 2011, when Craig Mackail-Smith scored the only goal of the game.