De Rossi has been linked with a move away from the Stadio Olimpico with Chelsea reportedly keen on the 29-year-old Italy international.
But when asked about the star's future, Garcia told reporters: "He is a great player and surely it's better to have him with us than to see him leave."
Garcia appeared more relaxed about the future of Pablo Osvaldo and Marquinhos, adding: "They are still with us, we would like to keep the best players. But if they were to leave, we will replace them.
One player who will be joining Roma is goalkeeper Lukasz Skorupski after the 22-year-old passed a medical and signed a contract with the Serie A side on Friday.
Skorupski has played over 50 games in the Polish Ekstraklasa for Gornik Zabrze, gaining himself a reputation as a solid and promising goalkeeper.