The Eagles have not won on the road since they beat Peterborough in November, a winless run that was stretched to 10 matches by Saturday's 1-0 defeat at Sheffield Wednesday.
However, they remain just four points off the automatic promotion places and Holloway expects plenty of twists and turns before the end of the season.
He said: "It's an unpredictable league. I think Reading were sixth this time last year.
"But we have to get our away form sorted out as we haven't won since Peterborough and that was thanks to two late goals, coming from behind.
"There's no reason why we can't win away. If you read the stats we were pretty comfortable but we didn't turn it into a goal. It was just the last pass that let us down."