The Seasiders booked their trip to Goodison Park thanks to the easiest of victories in Tuesday night's fourth-round replay at Hillsborough, which came courtesy of first-half efforts from Matt Phillips and Lomana LuaLua and a Ludovic Sylvestre strike after the interval.
All three goals were from the top drawer and after an incisive attacking display, Holloway wants his side to reproduce that form on Merseyside.
"We have to try and replicate that at his place against his team," he said when asked what Toffees manager David Moyes would have thought of Tuesday night's performance.
"They beat us 5-3 at their place last season and we drew 2-2 at ours and they kept their status and we didn't.
"We have to go there, a very tough place to go and they will be favourites, but let's see what we can do.
"We have got some unbelievably exciting games before that, though."
Holloway made eight changes to his side, who are currently fifth in the Championship, and he admits that the showing of his second-string players has caused some confusion in his mind.
"I thought we were as professional as we have been since I've been here," he said.
"The goals we scored, the way we defended and then attacked, we didn't get them much of an opportunity.
"I was delighted for myself and the team I picked and some of those performances are going to cause me some problems in the future because is my team as obviously weakened when I make so many changes?
"I don't think anyone could tell me my best team now and I don't think I know either and that's what makes me proud.
"I thought we looked like a foreign team rather than an English team with the way we passed it."
Wednesday boss Gary Megson insisted he wanted to progress but was happy to now concentrate on their quest to earn promotion from League One.
"We certainly wanted to win but everything at this football club points to being successful in the league and we are not strong enough to beat Yeovil, take on a strong Blackpool side and then go to Exeter (on Saturday)," he said.
"We had to chop and change the team.
"If anybody would have said to me your playing three games in the next seven days which two do you want to win, I would have said the two league games.
"Our priority has to be the league and we now have to pitch up and put in a performance at Exeter."
Despite going behind in the seventh minute, the Owls could have been ahead Ryan Lowe's early miss as his side squandered the chance to take a fifth-minute lead.
And Megson felt that was an important moment.
"We had a great opportunity in the first few minutes and if that goes in, I'm not saying the result would have been different, but I think our performance would be different," he said.
"They took their goals brilliantly and I thought they were a class act with the way they kept the ball."
