Worthington revamped his squad during the summer, with nine new arrivals and 10 players leaving Bootham Crescent and does not envisage any further business before September 1 unless injuries force his hand.
"I'm more than happy now to run with what we've got," Worthington said.
"There has been a lot of movement both in and out during the summer and we'll focus now on gelling this group of players.
"There's a good mix of young and experienced players and unless we get a couple of key injuries we won't be adding any more."
Worthington's side have taken four points from their first three league games and chase their second win at Bristol Rovers on Saturday.
"Bristol Rovers will not be easy," he added. "John Ward is an experienced campaigner and his team will be very well organised.
"Our players will have to fight for everything, as they did against Hartlepool last week, but if we compete like that again it's a game we can win."