Second-half finishes from Tom Soares and William Edjenguele helped end the Chairboys' three-game unbeaten run, but Lewis is confident his side can get back to winning ways against Stanley.
He told the club's official website: "It's a disappointing result and, as a group, we were looking at the next two as being positive ones, but hopefully we'll put that right at Accrington.
"We'll be positive and we'll be working our socks off this week to try and get the three points.
"From defeats you always have to take pointers and look at things that you can put right. As a group and Gaz (Ainsworth, manager) as a person, we are always positive for the next game.
"We're a good group and there will be no-one with their chins on the floor, we won't let that happen. We'll be raring to go Saturday."