One of the changes is enforced with Barry Corr beginning a three-match ban after being sent off in Saturday's 2-1 defeat.
And with Adam Stansfield (knee) and Richard Logan (calf) still rated doubtful, Craig McAllister and James Norwood - who both came off the bench to feature at Elland Road - are pushing to replace Corr in the starting line-up.
Otherwise, Tisdale is likely to resist the temptation to make changes elsewhere after admitting he was pleased with his side's efforts in their first game following promotion.
He handed debuts to new full-backs Richard Duffy and Scott Golbourne and they should keep their places.
