Former Ipswich striker Dean Bowditch is ruled out by a shoulder injury after marking his Glovers debut with the 23rd-minute opener in Saturday's 2-0 home league win over Tranmere.
That means Sam Williams - who replaced Bowditch in the 51st minute at the weekend - is poised to come in and make his full debut for the club.
Williams joined Yeovil in summer from Aston Villa and had a shot cleared off the line during Saturday's win.
He is likely to be paired with Gavin Tomlin, who scored Yeovil's second goal with a 75th-minute penalty against Rovers.
