Boothroyd raided his former club Watford to land the midfielder on loan earlier this week.
O'Toole could go straight into the starting line-up if Kem Izzet fails to overcome a slight back problem.
Defenders Marc Tierney and Pat Baldwin were rested for the midweek Johnstone's Paint Trophy defeat at Gillingham with minor niggles and should return to the back four.
Right-back Lee Beevers is still missing with a shoulder injury so Alan Maybury keeps his place.
Striker Steven Gillespie is back in training following his latest hamstring trouble but will not be rushed back, while Jamie Guy and Paul Reid are continuing to recover from knee operations.