Taylor is nursing a hamstring strain and Coloccini has been struggling with a groin problem but both players will be given time to shake off their respective injury problems.
Hughton has been boosted after Marlon Harewood and Jose Enrique were passed fit to face Billy Davies' men after recent knocks.
The Magpies will face a Forest side that have won their last three fixtures and Hughton told the Newcastle Evening Chronicle: "Their early season form wasn't so good but they are in very good form now and will be looking forward to taking us on.
"They have a lot of good options around the pitch and we expect a tough game."
