Kirkland is a strong doubt for the game after sustaining a recurrence of a back spasm in the first half of last week's defeat to Birmingham.
If he doesn't make it then both Mike Pollitt and Richard Kingson are on standby to deputise.
Manager Roberto Martinez is forced into one definite change as Hendry Thomas serves a one-match ban, with Jordi Gomez the player most likely to step into the breach.
Latics (from): Kirkland, Edman, Bramble, Scharner, Melchiot, Figueroa, Boyce, N'Zogbia, Diame, Scotland, Koumas, Sinclair, Cho, Rodallega, Amaya, De Ridder, Gomez, McCarthy, Kingson, Pollitt.
Kick off is 12.45pm.