Johnson has been sidelined with a groin injury since October and misses out along with Simon Davies (ankle), Seol Ki-Hyeon (leg) and Diomansy Kamara, who has been to France for more treatment on his knee injury.
Roy Hodgson's team is likely to contain several changes from the side that beat Basle on Wednesday, with Damien Duff, Brede Hangeland and Clint Dempsey all likely to start.
Fulham (from): Schwarzer, Zuberbuhler, Konchesky, Pantsil, Hangeland, Baird, Smalling, Kelly, Hughes, Etuhu, Murphy, Dempsey, Gera, Riise, Greening, Duff, E Johnson, Nevland, Zamora.
