The in-form French midfielder suffered an ankle knock during Wednesday night's Johnstone's Paint Trophy win over Norwich and is doubtful, so Paul Wotton stands by.
Defender Radhi Jaidi and striker David Connolly should return to the starting line-up after being rested in midweek.
Goalkeeper Kelvin Davis is getting closer to a return after a groin injury but may not be risked at Elland Road, with Bartosz Bialkowski likely to keep the gloves again.
Veteran full-back Graeme Murty is the only other absentee with ankle ligament damage.
Saints will set a new post-war club record if they avoid defeat - extending their unbeaten run away from home to 11 matches.