Van Aanholt has joined the club for a month as cover for Jose Enrique, who is facing several weeks on the sidelines with a hamstring injury.
The 19-year-old is the second signing of the day after the loan signing of QPR defender Fitz Hall, who could also feature at the Walkers Stadium.
It is not all good news for the Magpies, however, with Chris Hughton revealing Steven Taylor could be out of action for up to two months with a knee injury.
The England Under-21 international has medial ligament damage, but he does not require surgery at least.
Danny Simpson (ankle) and Shola Ameobi (shoulder) are also unavailable for Saturday's game, but Jonas Gutierrez has recovered from a knock to his ankle in midweek.
In addition, Joey Barton will return to full training next week for the first time since suffering a foot injury back in September.
Kick-off in the East Midlands is at 5.20pm.