The Scotland international sustained a head injury in Tuesday's 1-0 win at Peterborough.
Ferguson, who is searching hard for new signings, said: "He was knocked out so it's a mandatory 10 days that he will have to miss."
On-loan Manchester United striker Danny Welbeck is in line to make his home debut after playing 89 minutes at London Road in midweek.
Neil Mellor scored the winning goal against Posh and impressed in a wide position on the right flank which he looks set to retain.
But former Cardiff winger Paul Parry remains sidelined with a knee problem while midfielder Barry Nicholson (broken leg) is a long-term absentee.