The striker returned from a hernia operation as a substitute towards the end of the 5-0 midweek drubbing at Nottingham Forest.
Vine could get the nod alongside Jay Simpson after the Arsenal loanee endured a tough evening up front on his own at the City Ground.
Winger Lee Cook was on the bench on Tuesday night for the first time this season after recovering from summer knee surgery and will hope to get on the pitch.
Kaspars Gorkss, Damion Stewart and Matt Connolly will vie for two spots at centre-half following Fitz Hall's switch to Newcastle.
Goalkeeper Carl Ikeme has extended his loan spell from Wolves until April and will get the nod ahead of Radek Cerny again.