Irvine is likely to stick with the same starting line-up that overcame Blackpool 2-0 with Marcus Tudgay continuing to partner Luke Varney in attack in Tuesday night's Championship clash at Hillsborough.
Midfielder Tommy Miller returned to first-team training last week having been sidelined with a hamstring injury but he will not yet be considered for first-team action.
Defender Lewis Buxton and midfielder Jermaine Johnson (both hamstring) remain out.
Irvine has an unbeaten home record since taking over the Owls hotseat in January with three victories in three after defeating Peterborough, Plymouth and Blackpool.
Doncaster ran out 1-0 winners the last time these two sides met in December with Rovers' current top scorer Billy Sharp - on loan from Sheffield United - grabbing the only goal.