The duo both picked up groin problems during their 2-0 victory over Yeovil on Saturday and are major doubts.
Should they not be passed fit Darren Randolph and Jose Semedo are the most likely to replace them in Parkinson's first XI.
Midfielder Johnnie Jackson was handed a starting role against Yeovil and should retain his place in Parkinson's side after joining on loan from Notts County.
Charlton will definitely be without Grant Basey who remains sidelined with ankle ligament damage, while Kelly Youga is still missing with a knee injury.
Striker David Mooney showed no ill-effects following a head injury against the Glovers and should keep his place in attack alongside Deon Burton.