Nineteen-goal striker Paynter returned from a hamstring injury to play the final half-hour of last weekend's 1-0 win at Hartlepool but should be okay to start from the off this time around.
Defender Cuthbert, meanwhile, made his comeback on the bench after medial ligament trouble and he will now compete with Jean-Francois Lescinel for a starting berth at Elland Road.
Vincent Pericard (hamstring) and Sean Morrison (groin) are both 50/50 for the trip to Yorkshire having returned to full training.
But should the pair not make it against Leeds then they will certainly be in the frame for Monday's home clash against Tranmere.
Callum Kennedy is close to 100% after his lengthy spell on the sidelines but Kurt Hammonds (knee) and Alan O'Brien (hamstring) remain in recovery.