The Chairboys were thumped 6-0 at the Galpharm live on television last November and Waddock will be hoping for a massively improved performance at Adams Park.
Waddock's side have drawn their last four games but remain seven points short of getting out of the League One drop zone.
Centre-half Leon Johnson is still out as he recovers from surgery on his hip injury while midfielders Lewwis Spence (knee) and Ian Westlake (knee) are also sidelined.
Chris Westwood, Kevin Betsy and Matt Harrold are likely to be the only three players who started the thrashing in Yorkshire to start the rematch.
