The changes may come despite having gained an invaluable three points with a 3-1 win at Leyton Orient in League One on Saturday.
Gary Liddle scored either side of Roy O'Donovan's strike to give the Pools a commanding 3-0 lead at the break.
And although substitute Adrian Patulea netted a consolation, it was not enough to prevent Hartlepool from securing their fourth away win of the season and three points that ended up costing Orient boss Geraint Williams his job.
Speaking before Williams parted ways, Turner said: "It was a six-pointer as Orient are in the same position as we are. They have got one less home game and they are on a bit of a run that is not very nice to be on but I think Orient will survive from what I have seen."
He added: "If you perform then the results will come. It's when you don't perform and keep getting hammered three's and four's, that's when you are in trouble. We've had three really bad games this season and got whipped in all of them, but in the other games we were fantastic.
"I think it's between eight or nine clubs as to who goes down. We have a very tough game against Brighton on Monday and, as I said to the players if they were to win 5-0 at Orient, I will still make changes because we have to be on the pace and we will need some fresh legs."