The Addicks' 13-goal top scorer failed a fitness test on his groin injury ahead of Saturday's defeat at Southampton, which dented their hopes of automatic promotion.
Rob Elliot (groin) is still out so Darren Randolph continues in goal while full-backs Grant Basey (ankle) and Kelly Youga (knee) and forward Leon McKenzie (thigh) remain on the sidelines.
Valley boss Parkinson, who guided the Us to promotion from League One in 2006, must decide whether to recall teenage midfielder Jonjo Shelvey after dropping him to the bench at St Mary's.
Scott Wagstaff, David Mooney and Akpo Sodje are also pushing for recalls.
