Roy Hodgson will give late fitness tests to Danny Murphy (calf), Paul Konchesky (knee) and Bobby Zamora (Achilles) while Andrew Johnson (shoulder), Simon Davies (foot) and Toni Kallio (Achilles) are out.
Greening could make his debut but fellow new signing Kagisho Dikgacoi, who completed a move from South African club Golden Arrows on Thursday, is still lacking match fitness.
Kick-off at Villa Park on Sunday is at 4pm.
Fulham (from): Zuberbuhler, Schwarzer, Stockdale, Konchesky, Stoor, Pantsil, Hughes, Hangeland, Kelly, Baird, Smalling, Duff, Andranik, Riise, Dempsey, Etuhu, Greening, Nevland, Kamara, Zamora, Johnson, Seol.
