Otsemobor has missed the last four games - all victories - with a hamstring injury he sustained in the 1-1 draw at Gillingham on September 26.
Goalkeeper Declan Rudd and midfielder Stephen Hughes are back in the squad after international duty with England Under-19s and Scotland respectively.
But defenders Michael Spillane (hamstring) and Michael Nelson (ankle) remain sidelined along with midfielder Owain Tudur Jones (calf).
Fellow midfielder Matty Gill returned with a 45-minute run-out in the reserves' 7-0 thrashing of Stevenage in midweek but is not yet ready to be considered.
Manager Paul Lambert told the club's official website: "We'll go there and try to win. We're playing really well at the minute and if we go there and play the way we have been then we'll be right in the game. We'll need to go there and defend strongly."