Jamie Carragher, Glen Johnson and Jose Reina were all rested for the Champions League defeat by Fiorentina on Wednesday but are expected to face the Gunners.
Benitez must decide whether Alberto Aquilani is ready for a Premier League starting role, despite facing his fellow Italians in midweek.
Fernando Torres is likely to lead the attack for the first time since the draw in Lyon on November 4. Lucas Leiva and Fabio Aurelio are also likely to return.
Kick-off is at 4pm.
Liverpool (from): Reina, Johnson, Carragher, Agger, Insua, Benayoun, Gerrard, Mascherano, Aquilani, Kuyt, Torres, Cavalieri, Lucas, Aurelio, Skrtel, Riera, Kyrgiakos, Ngog, El Zhar.