The Magpies boss rotated his ranks for the club's two recent FA Cup encounters against Plymouth but that policy will certainly be ditched as attention switches back to league matters, with Nottingham Forest now also breathing down their necks.
Peter Lovenkrands netted a hat-trick to see off the Pilgrims 3-0 in their midweek replay but he will not be available having returned to Denmark for family reasons.
Alan Smith has fully recovered from an eye injury sustained during the initial goalless draw at Home Park and should start.
Fellow midfielder Joey Barton remains the only player on the injury list as he nears the end of his lengthy recovery from a foot injury.
On-loan full-back Danny Simpson is due to make his final appearance for the club before returning to Manchester United although Hughton is still trying to negotiate a permanent deal.