The Manchester United midfielder has not played for his country in 2011 and has only played two competitive games since the beginning of March because of a virus.
Christophe Berra has been preferred to Danny Wilson as partner to Gary Caldwell in the heart of Craig Levein's defence.
Aston Villa's new signing Alan Hutton makes his first start of the season but there were few surprises with Kenny Miller leading the line as expected.
Scotland team to face the Czech Republic in Saturday's Euro 2012 qualifier at Hampden, confirmed by the Scottish Football Association: McGregor, Hutton, Caldwell, Berra, Bardsley, Naismith, Fletcher, Adam, Brown, Morrison, Miller.
