O'Hara is absent with a back problem and there are doubts over whether he will be fit for the club's FA Cup Final date with Chelsea on May 15. Aaron Mokoena is struggling with a groin problem but hopes to feature.
The likes of Hassan Yebda (knee), Kevin Prince Boateng (ankle), Nadir Belhadj (thigh), Papa Bouba Diop (knee) and Tommy Smith (broken nose) may miss out as they are still struggling for fitness.
Aruna Dindane is still unable to play as Pompey have been unable to reach a deal with his parent club Lens to use him in their remaining Premier League games.
Pompey (from): James, Ashdown, Mullins, Piquionne, Brown, Kanu, Basinas, Vanden Borre, Mokoena, Rocha, Smith, Hughes, Utaka, Sowah, Ward, Wilson, Ritchie.