The Ivory Coast international appeared in Sunday's FA Cup semi-final triumph over Tottenham but Pompey are unable to pay his parent club Lens the £4million they are owed if he plays one more game.
Right-back Anthony Vanden Borre returns from suspension but Hassan Yebda (knee), Kevin Prince Boateng (ankle), Nadir Belhadj (thigh), Papa Bouba Diop (knee), Tommy Smith (broken nose) and Aaron Mokoena (groin) may be rested.
Portsmouth (from): James, Ashdown, Mullins, Piquionne, Finnan, O'Hara, Brown, Diop, Kanu, Basinas, Vanden Borre, Belhadj, Mokoena, Rocha, Smith, Yebda, Boateng, Hughes, Utaka.
