The Silkmen opened their campaign with a 2-2 draw at Stevenage on Saturday and are again expected to be without Ricky Sappleton, Paul Morgan and Ross Draper.
But midfielder Hamza Bencherif is edging closer to full fitness and was among the substitutes at Broadhall Way.
And manager Gary Simpson sees no reason why side cannot defy the odds and cause an upset against Paulo Sousa's npower Championship outfit.
The Foxes lost 3-2 at Crystal Palace on Saturday and Simpson said: "We are of course going there as underdogs, but you never know what can happen on the day and perhaps we can cause a shock."
