New signing Marvin Emnes is likely to be in contention for his Swansea debut.
The Middlesbrough man, who can play out wide or in attack, signed a one-month loan deal with the Swans on Monday morning and the south Wales outfit are expected to have the relevant paperwork and clearance granted in time for the Liberty Stadium clash.
Manager Brendan Rodgers will check on midfielder Mark Gower although he could well miss the encounter having been forced out of Saturday's 1-0 win at Reading after just 20 minutes with a hamstring injury.
David Cotterill - returning alongside fellow key midfielders Scott Sinclair and Darren Pratley - replaced Gower at the Madejski Stadium and is favourite do so again if required.
Rodgers will also assess the fitness of Joe Allen and Kemy Agustien. The former failed to recover from a groin problem in time to be considered for the weekend trip to Berkshire while Agustien has recovered from his knee injury but is lacking match fitness.
QPR manager Neil Warnock has lost key midfielder Akos Buzsaky for the trip.
The 28-year-old went off with a knee injury during Saturday's goalless draw with Norwich and is set to have a scan this week.
That could pave the way for Alejandro Faurlin, who recently recovered from a hamstring injury, to play, although Mikele Leigertwood is more likely to get the nod having replaced Buzsaky on Saturday.
Gavin Mahon could also feature having been handed a one-month contract by Warnock, but Peter Ramage and Lee Cook remain long-term absentees with knee injuries.