Chelsea will welcome back defender Jose Bosingwa for his first start since last October against Wolves.
The right-back has fully recovered from knee problems that sidelined him for almost a year.
Striker Didier Drogba, who missed last week's Barclays Premier League clash against Aston Villa and the Champions League win over Spartak Moscow because of a virus, is fit again.
But Frank Lampard (groin), Alex (thigh), Yossi Benayoun (Achilles) and Ramires (ankle) are all sidelined with striker Daniel Sturridge (ankle) also doubtful.
Wolves manager Mick McCarthy will be without Michael Mancienne for the trip as the conditions of his loan mean he cannot face his parent club.
McCarthy will also be without suspended captain Karl Henry and defender Jody Craddock (hip) while the game is also likely to come too soon for Stephen Hunt as he continues his return from a foot injury.
Midfielder David Davis, 19, has been recalled from his loan with Walsall and goes straight into the squad.
Chelsea (from): Cech, Turnbull, Ivanovic, Bosingwa, Ferreira, Cole, Terry, Zhirkov, Essien, Obi, McEachran, Kakuta, Malouda, Anelka, Drogba, Kalou, Bruma, Mellis, Borini, Van Aanholt, Sturridge.
Wolves (from): Hahnemann, Foley, Berra, Ward, Jarvis, Jones, Van Damme, Fletcher, Doyle, Ebanks-Blake, Elokobi, Halford, Bent, Hennessey, Edwards, Milijas, Stearman, Mouyokolo, Mujangi Bia, Davis.