Preston boss Darren Ferguson looks set to be boosted by the return of midfielder Matty James.
The on-loan Manchester United youngster has been sidelined for the past six weeks with a damaged ankle.
United have been overseeing the 19-year-old's recovery from a damaged ankle tendon and Ferguson said: "I should think Matt will be fit."
Striker Josh King, also on loan from Old Trafford, was substituted at the interval during Tuesday's 3-2 home defeat to Scunthorpe after twisting his ankle late in the first half.
It was the same ankle which he damaged at Burnley last month and he will be assessed but defender Wayne Brown has been absent with a hamstring injury and looks set to remain sidelined.
The trip to Preston is likely to come too soon for Darren Ambrose and Sean Scannell.
The attacking duo have returned to training following long spells on the sidelines, but are not expected to feature at Deepdale.
Ambrose, last season's 20-goal top scorer, has been missing for two months with a badly bruised leg, while winger Scannell suffered a knee injury in pre-season.
Full-back David Wright, who managed just one appearance since his summer switch from Ipswich before picking up a calf injury, was on the bench at Norwich on Tuesday and could be involved again.
Centre-half Claude Davis serves the second game of his four-match ban following his red card against Millwall last weekend.
Defender Lee Hills and midfielder Neil Danns (both knee) are still missing.
