Key midfielder Charlie Adam is a major doubt for the home date with Wolves.
Adam suffered a medial ligament strain playing in Scotland's victory over the Faroe Islands on Tuesday and looks likely to miss out.
Ghana international Richard Kingson will continue in goal with Matt Gilks ruled out for up to two months with a broken kneecap. Youngster Mark Halstead has been recalled from a loan at Barrow as back-up.
Blackpool have no other new fitness concerns but are still missing long-term casualties Billy Clarke, Alex Baptiste and Louis Almond.
Wolves defender Christophe Berra is set to return for the clash.
The Scotland defender was forced to withdraw from last weekend's home defeat against Bolton shortly before kick-off with a sore knee.
Fellow centre-back Steven Mouyokolo has also been declared fit after suffering a knee injury in the early stages against the Trotters although he was able to complete the game.
Winger Matt Jarvis is expected to be fit despite missing part of training this week with a calf injury.
Blackpool (from): Kingson, Eardley, Cathcart, Crainey, Evatt, Adam, Vaughan, Varney, Taylor-Fletcher, Cambell, Grandin, Harewood, Phillips, Edwards, Carney, Euell, Sylvestre, Keinan, Southern, Basham, Ormerod, Halstead.
Wolves (from): Hahnemann, Foley, Stearman, Berra, Mouyokolo, Elokobi, Hunt, Henry, Milijas, Jarvis, Ebanks-Blake, Doyle, Hennessey, Van Damme, Ward, Jones, Bent, Mancienne.