Charlton will be without captain Christian Dailly when they host Bristol Rovers.
The veteran defender starts a four-match ban after being shown his second red card of the season against Yeovil on Saturday.
Despite claiming the incident, a challenge with Glovers striker Sam Williams, was merely a clash of heads manager Phil Parkinson has opted not to appeal against the decision.
Jonathan Fortune or Miguel Llera will step in alongside Gary Doherty at centre-half.
Striker Joe Anyinsah could return after missing the last two matches with a groin injury, while winger Scott Wagstaff sat out at the weekend through illness and will be checked over.
Full-backs Chris Solly (ankle) and Kelly Youga (knee) remain long-term absentees.
Bristol Rovers manager Paul Trollope will be without Byron Anthony.
Anthony picked up his fifth caution of the season in the draw with Brighton and serves a one-match ban.
Carl Regan is also suspended, serving the second game of his three-match ban while youngster Charlie Reece is still sidelined with a rib injury.
Stuart Campbell faces a late fitness test after suffering a knock to his ankle while John Akinde is fully fit.
Will Hoskins returned as a substitute at the Withdean, three weeks earlier than expected following a nasty ankle injury and will be assessed before Rovers name their squad.
James Tunnicliffe is expected to return to Trollope's defence after he was ineligible against parent club Brighton at the weekend.