City midfielder Yaya Toure is expected to return to the squad against Bolton following a migraine.
Manager Roberto Mancini looks likely to shuffle his pack again following the Europa League victory over Salzburg, when he made eight changes from the side that drew with Stoke.
Mario Balotelli took his tally to five goals from four starts in midweek and could be paired with Carlos Tevez, who was rested.
Bolton manager Owen Coyle will monitor the fitness of midfielder Stuart Holden ahead of the trip to Eastlands.
Holden only returned to training on Thursday after sitting out the draw with Blackpool because of a thigh strain.
The American's replacement Mark Davies could retain his place after scoring a superb equaliser last weekend.
Manchester City (from): Hart, Richards, Bridge, Lescott, Boyata, De Jong, Vieira, Barry, Johnson, K Toure, Y Toure, Tevez, Silva, Adebayor, Balotelli, Kolarov, Given, Milner, Kompany, Boateng, Logan, Cunningham.
Bolton (from): Jaaskelainen, Bogdan, Cahill, Steinsson, Knight, Robinson, Lee, Holden, Muamba, Petrov, Cohen, K Davies, Elmander, M Davies, Blake, Taylor, Klasnic, Ricketts, Alonso, Moreno.