Blackburn will have Roque Santa Cruz available, but the striker is likely to be on the bench.
Goalkeeper Paul Robinson is fit to return after a calf injury and Steven Nzonzi (hamstring) could be back in contention.
Nikola Kalinic is back from suspension while Gael Givet and Martin Olsson have overcome knocks. Vince Grella, Keith Andrews and Phil Jones remain on the sidelines and Brett Emerton is on international duty with Australia.
Didier Drogba, Florent Malouda, Michael Essien and Ashley Cole could all return to the Chelsea side.
The quartet were all rested for Sunday's 7-0 FA Cup third-round thrashing of Ipswich and manager Carlo Ancelotti must decide whether to recall them against Rovers.
Ancelotti has no new injury concerns, with Alex, John Obi Mikel (both knee), Yury Zhirkov (calf) and Yossi Benayoun (Achilles) all still sidelined.
Chelsea (from): Cech, Ferreira, Bosingwa, Ivanovic, Bruma, Terry, Cole, Ramires, Kalou, Essien, Lampard, Anelka, Sturridge, Drogba, Malouda, Turnbull, Van Aanholt, McEachran, Mellis.
Rovers (from): Robinson, Nelsen, Samba, Givet, Olsson, Salgado, Pedersen, E-H Diouf, Dunn, Benjani, Hoilett, MB Diouf, Nzonzi, Kalinic, Doran, Morris, Hanley, Goulon, Lowe, Bunn.