Huddersfield will be without goalkeeper Alex Smithies and defender Tamas Kadar again.
Terriers manager Lee Clark has no new injury or suspension worries, but could be tempted to make changes following his side's 4-0 midweek defeat at Carlisle in the first leg of their northern area Johnstone's Paint Trophy final.
Smithies and Kadar, on loan from Newcastle, missed out on Tuesday night due to respective knee and hamstring injuries, but defender Liam Ridehalgh is expected to shake off illness and return to the squad.
Clark is still without defenders Gary Naysmith (toe) and Leigh Franks (hamstring) and midfielder Damien Johnson (knee ligaments) as his side look to extend their unbeaten league run to five matches.
Experienced goalkeeper Nick Colgan will go straight into the squad after signing a short-deal deal having joined from Grimsby.
Steven Gillespie is pushing for his first start of the season.
The striker, Colchester's record signing, put an injury-hit campaign behind him when he scored twice as a substitute in last week's 2-1 win over Bournemouth.
Boss John Ward could also add recent signings Conor Powell and Matthias Vilhjalmsson to his squad now that they have had a weeks' training under their belts.
Ben Coker made his full debut at left-back against the Cherries and looks set to keep his place after an impressive display.
Defenders Magnus Okuonghae, Brian Wilson (both ankle) and Morten Knudsen and midfielder John-Joe O'Toole (both knee) are still on the sidelines.