New loan signings Eidur Gudjohnsen and Gael Kakuta could make their first appearances for the Cottagers.
Gudjohnsen has been registered after completing his loan move from Stoke late on Monday night while Kakuta missed Sunday's 4-0 win over Tottenham as he was cup-tied.
David Stockdale is likely to continue in goal as Mark Schwarzer is tired after his exploits with Australia in the Asian Cup and Dickson Etuhu is a doubt with a hamstring injury.
Newcastle new boy Stephen Ireland will not figure in the match after arriving on Tyneside with an injury.
The midfielder, who has joined on loan from Aston Villa for the rest of the season, has a hamstring problem which is expected to sideline him for around two weeks.
Midfielder Cheik Tiote completes his three-match ban but skipper Kevin Nolan (ankle) and Danny Guthrie, who limped off with cramp during the 1-1 draw with Tottenham last time out, will be available.
Ryan Taylor (ankle), has returned to training, but Steven Taylor (hamstring), Dan Gosling (knee), Alan Smith (ankle) and Hatem Ben Arfa (broken leg remain on the sidelines.
Fulham (from): Stockdale, Pantsil, Hangeland, Hughes, Baird, Davies, Riise, Murphy, Sidwell, Etuhu, Duff, Dempsey, Gudjohnsen, Kakuta, Kamara, Gera, Dembele, Etheridge, Salcido, Greening, A Johnson, Halliche.
Newcastle (from): Harper, Krul, Simpson, Perch, Ferguson, Enrique, Coloccini, Williamson, Campbell, Barton, Nolan, Gutierrez, Guthrie, Vuckic, Donaldson, Ameobi, Lovenkrands, Best, Ranger.