Tim Cahill will return for Everton in the clash against the Seasiders.
The Australia midfielder has been missing for the past month due to the Asian Cup but, after being rested in midweek, is now ready to step back into the side.
Phil Jagielka is in contention to start after making his first appearance since recovering from a thigh strain off the bench at Arsenal on Tuesday.
Everton have no fitness concerns with Tony Hibbert available again after illness.
Blackpool manager Ian Holloway will give fitness tests to captain Charlie Adam and midfielder David Vaughan.
Adam (calf) and Vaughan (knee) both suffered knocks in Wednesday's 3-1 defeat against West Ham while Stephen Crainey (ankle) is definitely out.
Andy Reid was the only one of Holloway's four new signings to start at Bloomfield Road in midweek so James Beattie and Jason Puncheon will be hoping to join him but Sergei Kornilenko is not yet match fit.
Everton (from): Howard, Neville, Distin, Jagielka, Heitinga, Baines, Coleman, Cahill, Fellaini, Osman, Rodwell, Arteta, Bilyaletdinov, Saha, Beckford, Anichebe, Gueye, Hibbert, Baxter, Mucha.
Blackpool (from): Kingson, Eardley, Cathcart, Evatt, Adam, Carney, Phillips, Vaughan, Varney, Taylor-Fletcher, Campbell, Sylvestre, Grandin, Euell, Beattie, Reid, Puncheon, Ormerod, Edwards, Baptiste, Southern, Rachubka, Harewood.