Inverness are hopeful that both Jonny Hayes and Aaron Doran will make the clash.
Hayes suffered a minor reaction to a foot problem after returning during the midweek defeat by Dundee United while Doran is rated 50-50 after suffering a hip injury in the game.
David Proctor (hamstring) and Dani Sanchez (hand) are again on the sidelines.
Motherwell welcome their captain Stephen Craigan back from suspension.
Steven Saunders is also in contention following a hamstring problem but Steve Jones will not make the trip despite returning to training following a hamstring injury. Bob McHugh (wrist) is also still out.
Inverness (from): Esson, Innes, Duff, Doran, Odhiambo, Foran, Rooney, Munro, Duncan, Sutherland, Hogg, MacDonald, Hayes, Ross, Cox, Tokely, Gillet, Morrison, Tuffey.
Motherwell (from): Randolph, Hateley, Gunning, Hammell, Hutchinson, Jennings, Lasley, Forbes, Murphy, Humphrey, Sutton, Jeffers, Meechan, Pollock, Casagolda, Craigan, Saunders, Hollis.