Millwall boss Kenny Jackett will have new signing Andros Townsend available for the clash but Darren Purse and Martin Rowlands will not feature.
Winger Townsend has joined the Lions on loan from Tottenham until the end of the season and goes straight into the squad to face the Championship leaders.
Centre-back Purse is unavailable as he starts a two-match ban after picking up his 10th yellow card of the season in the 1-0 defeat at Watford on Saturday, while on-loan Hoops midfielder Rowlands is ineligible to face his parent club.
Winger Hameur Bouazza missed out against the Hornets after picking up a knee injury in training and is still a major doubt.
Striker Josh McQuoid will be hoping to feature after returning to the squad at the weekend following a month out with an ankle injury.
Midfielder Jimmy Abdou is out until at least mid-April with a knee problem, while defender Jack Smith (thigh) and striker Shaun Batt (knee) are still sidelined.
QPR boss Neil Warnock has fitness doubts over defenders Fitz Hall and Danny Shittu ahead of the trip across the capital.
Hall had to come off in the first half of the 1-0 home win over Leicester on Saturday after injuring his hamstring and is a major doubt.
Warnock still has concerns over the overall fitness of Shittu and it remains to be seen whether he will stick with the Nigerian for his second game in four days.
Kaspars Gorkss and Matthew Connolly are in line to replace the duo if they are not passed fit.
Forward Tommy Smith was an unused substitute at the weekend after recovering from a hamstring problem and is set to get some game time against the Lions.
Defender Peter Ramage (cruciate) and strikers Patrick Agyemang and Jamie Mackie (both broken leg) are long-term absentees.