Derby hope Jamie Ward and John Brayford will be fit for the game.
Both players sustained injuries during the defeat at Middlesbrough in midweek.
Ward came off at half-time after complaining of a tight hamstring. The decision not to risk the on-loan striker in the second half prevented further damage and has given him a good chance of being involved on Saturday.
Defender Brayford, who is Derby's only ever-present this season, required lengthy treatment for an ankle knock at the Riverside but managed to complete the 90 minutes and trained on Wednesday.
James Bailey resumed training this week after a groin problem and the midfielder could return to the squad after a seven-match absence.
Defenders Dean Leacock (illness) and Russell Anderson (hamstring and calf) are also back in training but forward Tomasz Cywka (knee) is likely to remain on the sidelines as Derby look for a first home win in almost four months.
Swansea boss Brendan Rodgers is likely to freshen up his side for the clash as he looks to get their promotion charge back on track.
Rodgers admitted to being "the most disappointed I've been since I came to the club" following Tuesday's 1-1 home draw against Watford, a result which followed last weekend's 1-0 defeat at Scunthorpe.
Only similar struggles experienced by City's promotion rivals have seen them hang onto second spot, but Rodgers knows they cannot afford many more slip-ups.
Midfielders Darren Pratley and Leon Britton and striker Craig Beattie may come back into the starting line-up at Pride Park.
Rodgers will assess the fitness of skipper Garry Monk (knee) and midfielder Andrea Orlandi (thigh) after they both made their long-awaited returns to training at the start of this week, although it is unlikely either will be ready to start.