Charlton manager Chris Powell will be without striker Paul Benson when his side host Brentford.
The eight-goal striker will begin a four-match ban after being shown his second red card of the season during Tuesday night's 2-0 defeat against MK Dons for a dangerous tackle on midfielder Stephen Gleeson.
Top-scorer Bradley Wright-Phillips is likely to be restored to the starting line-up in Benson's place.
On-loan left-back Matt Fry returned to the squad in midweek and is pushing for a starting berth, but centre-back Gary Doherty will remain sidelined with a hamstring problem.
Midfielders Joe Anyinsah and Johnnie Jackson will also be missing with ankle and Achilles injuries respectively.
Powell himself will serve a one-match touchline ban after being charged with misconduct by the FA following comments he made after last Saturday's 1-1 draw with Tranmere.
Brentford boss Nicky Forster will be without Charlie MacDonald for the trip to Charlton.
The 10-goal striker returned from a dead leg in time to make the starting line-up against Brighton on Tuesday night, but had to be withdrawn after suffering ankle ligament damage following a challenge from Radostin Kishishev.
Robbie Simpson stepped off the bench to replace him and could start against the Addicks, although Lewis Grabban is another option.
On-loan Sunderland midfielder Adam Reed is set to continue following his full debut in midweek, but fellow midfielder Sam Wood is not yet ready to return from a broken arm.
Winger Myles Weston could return to the starting line-up as the the Bees look to avoid a third consecutive defeat.