Crystal Palace captain Patrick McCarthy is suspended following his sending-off against QPR last weekend so Claude Davis could be brought in to face his old club.
Midfielder Alex Marrow has suffered a setback in his recovery from an ankle injury after it flared up again this week.
And defender Lee Hills remains sidelined following the double leg break he sustained last season, although he could return before the end of the season.
Dougie Freedman is unlikely to make any unforced changes to the side that lost at Loftus Road.
Relegation-threatened Palace will be looking to extend their unbeaten run at home to 12 matches.
Derby, meanwhile, could welcome James Bailey and Russell Anderson back into their squad.
Midfielder Bailey has been out since the start of February with a groin injury, while central defender Anderson resumed full training last week after a four-month lay-off with a hamstring injury.
Fellow defender Dean Leacock, who was an unused substitute during the home win over Swansea last weekend, has been struggling with illness of late.
The trio all played for the reserves on Wednesday and may be included on the bench.
Midfielder Paul Green was struggling with illness ahead of the win against the Swans and was forced off early in the second half but is fit to face Palace, while Polish forward Tomasz Cywka (knee) and defender Jake Buxton (Groin) definitely miss out.